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Relapse and Recovery: from Mechanistic Understanding to Translational Research
Overall theme: relapse and recovery, with an emphasis on integration of preclinical and clinical research and leveraging insights from big data approaches. The symposium will highlight notable studies in drug and alcohol research, in areas ranging from molecular mechanisms to treatment in clinical populations.
Chairs: |
John Matochik, Ph.D., National Institute on Alcohol Abuse and Alcoholism [NIAAA] Roger Sorensen, Ph.D., National Institute on Drug Abuse [NIDA] |
8:30 – 8:45 a.m. |
Introduction and Opening Remarks Antonio Noronha, Ph.D., NIAAA Roger Little, Ph.D., NIDA George Koob, Ph.D. Director, NIAAA Nora D. Volkow, M.D., Director, NIDA |
8:45 – 10:45 a.m. |
Session I. Drug Memory and Molecular Drivers of Relapse Chair: Changhai Cui, Ph.D., NIAAA Speakers: Disrupting Drug Related Memories for Relapse Prevention Barry Everitt, Sc.D., F.R.S., F.Med.Sci., Downing College and Behavioural and Clinical Neuroscience Institute Bio Abstract Targeting mTOR Pathway to Disrupt Alcohol-related Memories Dorit Ron, Ph.D., University of California, San Francisco Bio Abstract Enduring Changes of the Stress System in Binge and Chronic Alcohol Consumption Thomas Kash, Ph.D., University of North Carolina at Chapel Hill Bio Abstract Distinct Opioid Receptor Mechanisms in the Protracted Heroin Abstinence Brigitte Kieffer, Ph.D., McGill University Bio Abstract |
10:45 – 11:00 a.m. | Break |
11:00 – 12:00 p.m. | Jacob P. Waletzky Memorial Award Lecture Introductory Remarks: Nora D. Volkow, M.D., Director, NIDA George Koob, Ph.D. Director, NIAAA Amygdala Dysregulation in Alcohol Dependence Marisa Roberto, Ph.D., The Scripps Research Institute Bio Abstract |
12:00 – 1:00 p.m. |
Joint NIDA-NIAAA Early Career Investigator Showcase [ECIS] Chairs: John Matochik, Ph.D., NIAAA Roger Sorensen, Ph.D., NIDA Erin Calipari, Ph.D. – NIDA AWARDEE Icahn School of Medicine at Mount Sinai Abstract Susan Ferguson, Ph.D. – NIDA AWARDEE University of Washington Abstract Elizabeth Glover, Ph.D. – NIAAA AWARDEE Medical University of South Carolina Abstract Jon Houck, Ph.D. – NIAAA AWARDEE University of New Mexico Jocelyn Richard, Ph.D. – NIAAA AWARDEE Johns Hopkins University Abstract Sarah Yip, Ph.D., M.Sc. – NIDA AWARDEE Yale University |
1:00 – 2:00 p.m. | Lunch (On Your Own) |
2:00 – 3:30 p.m. |
Session II. Circuit Mechanisms of Relapse Chair: Steve Grant, Ph.D., NIDA Speakers: Predictive Power of Insula Function in Prediction Relapse to Drug Addiction and Translational Potential Martin Paulus, M.D., Laureate Institute for Brain Research Bio Abstract Circuit Dysregulation and Rewiring in Alcoholism Edith Sullivan, Ph.D., Stanford University Bio Abstract Self-regulation of Pain and Underlying Circuitry Tor Wager, Ph.D., University of Colorado Boulder Bio Abstract |
3:30 – 3:45 p.m. | Break |
3:45 – 5:15 p.m. |
Session III. Relapse Risk and Treatment Chair: John Matochik, Ph.D., NIAAA Speakers: Peripheral and Prefrontal Stress System Dysfunction and their Joint effects on Relapse Risk in Alcoholism Rajita Sinha, Ph.D., Yale School of Medicine Bio Abstract Targeting Relapse-related Symptoms of Insomnia, Dysphoria, and Craving for the Treatment of Alcohol Dependence Barbara Mason, Ph.D., Scripps Research Institute Bio Abstract Findings from the International Quit and Recovery Registry Warren Bickel, Ph.D., Virginia Tech Carilion Research Institute Bio Abstract |
5:15 – 5:30 p.m. |
Discussion and Wrap-up George Koob, Ph.D. Director, NIAAA Nora D. Volkow, M.D., Director, NIDA |
5:30 p.m. | Adjournment |